Vitamin D test possibly disrupted in certain form of blood cancer

A standard blood test for vitamin D can give a distorted result in some patients. According to a report in the Nederlands Tijdschrift voor Hematologie, there may be an apparently elevated level of 25-hydroxyvitamin D in people with the blood cancer IgA-κ-multiple myeloma.

The disruption would arise from M-protein, an abnormal protein that occurs in the blood in this disease. The protein appears to influence the test method, making the outcome unreliable. The journal emphasizes that this concerns a specific subgroup of multiple myeloma.

Whether the finding also applies to other forms of the disease or other laboratory tests is not clear. Doctors and laboratories should be aware of this possible source of error, according to the source.

This report is a summary based on the mentioned source and is not medical advice. Consult a doctor or pharmacist in case of complaints.